Basically get to the highest level (70 was it?) and get 3 friends of equal level to go with you.
Have 2 killing the grubs, 2 aiming for his weak points.
Also run through the crimson armory to get some decent weapons beforehand.
Although me and my brother did it by ourselves. He was maximum level and I was like 50 something. I distracted all the grubs and stuff while he shot Crawmerax. I died several times, but got some great loot when we finished.
I was Roland, he was Mordecai.
Last edited by 4zb41; Oct 14, 2011 at 11:15 AM.