I've disenchanted all my wild cards except for the few that I've grown attached to, namely anything I used in mill decks.
I'm personally frustrated with C'thun. The minions that build up C'thun are all on curve, and they're all defensively stated, so they'll almost certainly trade well against early aggro, and they can be an absolute nightmare to remove as control or tempo. Furthermore, because playing C'thun cards builds up your late game, the deck is never really behind even if you do keep it down in the beginning because C'thun is basically a hard reset of tempo into their favor. Combined with the Twin Emperor of Bullshit with the other 10-power-C'thun cards, I just groan whenever I see a C'thun card get played because I know I'm not going to enjoy the match.