I still play this, and I'm still not bored.
Still amazed by the sheer graphic power and the different ways you can go with your character.
Complete fan of the series, can't wait till 3 comes out. Dying to continue the journey.
I felt that I enjoy the game the most on veteran, not too hard, but still challenging.
Insane was good too, but some parts were a bit too much, mostly the collector parts.
Played it on insanity the first playthrough, maybe that's why.
Also, I keep getting amused by all the amazing conversations some of the minor characters say.
Especially by Gabby and Donely ;P
The "Tank bred Krogan" in the Grunt rescue mission has some awesome lines as well.
If you take the time for the game, it really drags you in.
Definite 10/10 from me, even after almost 60 hours.
(Got all the expansions btw, Kasumi's mission is great, almost 007ish)