Holy shit, nobody said Secret of Mana!?
Duck Tales is in the first post. The fact that MegaMan isn't there perplexes me. Specifically, MegaMan II.
How about Zero and Legends? As for the Battle Network series, I have mixed feelings for it. It just doesn't feel like the Megaman I know.
And here's the most awesome Mgs songtrack :
Sad to say I own and play all your games to play xD
Monkey Island! =D